TiO2 나노튜브의 직경 및 길이에 따른 조골세포의 흡착 및 골형성능 효과
The Effect of TiO2 Nanotube Diameter and Length on the Adhesion and Osteogenic Functionality of Osteoblast
문경숙, 배지명, 오승한,
소속 상세정보
문경숙 ( Mon Kyoung-Sook ) - 원광대학교 치과대학 치과생체재료학교실
배지명 ( Bae Ji-Myung ) - 원광대학교 치과대학 치과생체재료학교실
오승한 ( Oh Seung-Han ) - 원광대학교 치과대학 치과생체재료학교실
KMID : 0362220100370020165
Abstract
The purpose of this study was to estimate the adhesion, proliferation, and osteogenic functionality of osteoblast cultured on the various diameter and length of TiO2 nanotubes. The tests of osteoblast adhesion, proliferation, and alkaline phosphatase activity resulted that there was no significant difference between nanotubes, but all values of osteoblast cultured on all kinds of nanotubes showed higher adhesion, proliferation, and alkaline phosphatase activity than those cultured on pure titanium as a control group (p<0.05). In terms of the influence of nanotube length on osteoblast behavior and osteogenic functionality, the increase of nanotube length reduced the initial adhesion and proliferation of osteoblast. Also, the results of alkaline phosphatase activity test showed same trend as those of cell adhesion and proliferation test, but all results did not show any significant difference between all experimental groups(p>0.05).
키워드
TiO2 nanotube; Osteoblast; Cell adhesion; Proliferation; Alkaline Phosphatase (ALP) Activity
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